Ren, a psychologically challenged Chihuahua, and Stimpy, less intelligent than your average cat, were created by John Kricfalusi and debuted on Nickelodon in 1991.
“The Ren & Stimpy Show” drew criticism from observers who deemed it unsuitable for children, citing its crass jokes and sexual innuendo. It aired for five seasons.
On Comedy Central, the show will join other adult-animation series including “South Park” and a revamped version of “Beavis and Butt-Head,” the channel said.
A debut date was not announced.